Activity of Species-specific Antibiotics Against Crohn's Disease-Associated Adherent-invasive Escherichia coli

Crohn's disease (CD) is associated with bacterial dysbiosis that frequently includes colonization by adherent-invasive Escherichia coli (AIEC). AIEC are adept at forming biofilms and are able to invade host cells and stimulate the production of proinflammatory cytokines. The use of traditional...

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Bibliographic Details
Published in:	Inflammatory bowel diseases Vol. 21; no. 10; pp. 2372 - 2382
Main Authors:	Brown, Carla L, Smith, Karen, Wall, Daniel M, Walker, Daniel
Format:	Journal Article
Language:	English
Published:	England 01-10-2015
Subjects:	Actins - metabolism Anti-Bacterial Agents - pharmacology Biofilms Colicins - pharmacology Crohn Disease - microbiology Endocytosis - drug effects Enzyme-Linked Immunosorbent Assay Escherichia coli Escherichia coli - drug effects Escherichia coli - isolation & purification Escherichia coli - physiology Escherichia coli Infections - drug therapy Escherichia coli Infections - microbiology Humans Macrophages - drug effects Macrophages - metabolism Macrophages - microbiology Tumor Cells, Cultured Tumor Necrosis Factor-alpha - metabolism
Online Access:	Get full text
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