Dengue virus surveillance in Singapore reveals high viral diversity through multiple introductions and in situ evolution

► The circulating dengue viruses in Singapore are highly diverse. ► Multiple importations and in situ evolution contribute to viral diversity in Singapore. ► In situ evolution could possibly result in viruses with improved fitness. Dengue fever, a vector-borne disease, has caused tremendous burden t...

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Bibliographic Details
Published in:	Infection, genetics and evolution Vol. 12; no. 1; pp. 77 - 85
Main Authors:	Lee, Kim-Sung, Lo, Sharon, Tan, Sharon Siok-Yin, Chua, Rachel, Tan, Li-Kiang, Xu, Helen, Ng, Lee-Ching
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier B.V 01-01-2012 Elsevier
Subjects:	Adaptation Aedes - virology Animals Arboviroses Biological and medical sciences Dengue - epidemiology Dengue - virology Dengue fever Dengue fevers Dengue Virus - classification Dengue Virus - genetics Dengue virus importations Disease Outbreaks Epidemiology. Vaccinations Evolution, Molecular General aspects Genetic Variation Genotype Human viral diseases Humans In situ evolution Infectious diseases Medical sciences Molecular epidemiology Phylogeny RNA, Viral - genetics Sequence Analysis, DNA Singapore Singapore - epidemiology Tropical viral diseases Viral diseases Viral Envelope Proteins - genetics Asia Singapore In situ evolution Dengue virus importations Molecular epidemiology Singapore Dengue fever Adaptation Multiple Dengue In situ Dengue virus Flavivirus Infection Virus Surveillance Viral disease Dengue group virus Arbovirus disease Evolution Flaviviridae
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