Role of retinoids in the prevention and treatment of colorectal cancer

Vitamin A and its derivatives, retinoids, have been widely studied for their use as cancer chemotherapeutic agents. With respect to colorectal cancer(CRC), several critical mutations dysregulate pathways implicated in progression and metastasis, resulting in aberrant Wnt/β-catenin signaling, gain-of...

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Bibliographic Details

Published in:	World journal of gastrointestinal oncology Vol. 7; no. 10; pp. 184 - 203
Main Authors:	Applegate, Catherine C, Lane, Michelle A
Format:	Journal Article
Language:	English
Published:	China Baishideng Publishing Group Inc 15-10-2015
Subjects:	A;β-catenin;Pho cancer;Retinoid;Vitamin Colorectal Topic Highlight Phosphatidylinositol-3-kinase Vitamin A β-catenin Peroxisome proliferator-activated receptor γ Phosphatase and tensin homolog deleted on chromosome 10 K-ras Colorectal cancer Retinoid Cyclooxygenase-2 P53
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