SARS-CoV-2 nucleic acid shedding is variable for every person

INTRODUCTIONConsidering the persistent positivity on RT-qPCR tests, the results of SARS-CoV-2 were monitored to evaluate the viral RNA shedding period. METHODSBetween March and June 2020, the sequential results of 29 healthcare workers' were monitored using RT-qPCR. RESULTSMore than 50% of the...

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Published in:Revista da Sociedade Brasileira de Medicina Tropical Vol. 54; p. e10622021
Main Authors: Lima-Morales, Daiana de, Wink, Priscila Lamb, Volpato, Fabiana Caroline Zempulski, Camargo, Joíza Lins, de-Paris, Fernanda, Barth, Afonso Luís
Format: Journal Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 01-01-2021
Sociedade Brasileira de Medicina Tropical (SBMT)
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Summary:INTRODUCTIONConsidering the persistent positivity on RT-qPCR tests, the results of SARS-CoV-2 were monitored to evaluate the viral RNA shedding period. METHODSBetween March and June 2020, the sequential results of 29 healthcare workers' were monitored using RT-qPCR. RESULTSMore than 50% of the individuals remained RT-qPCR positive after 14 days. Furthermore, this is the first study to describe positive RT-qPCR for SARS-CoV-2 in a healthcare worker with mild symptoms 95 days after the first positive test. CONCLUSIONSSequential RT-qPCR results were heterogeneous, and the viral RNA shedding period is unique for each person.
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Conflict of interest: The authors declare that they have no conflicts of interests.
Authors’ contribution: DLM, PLW, FCZV and ALB: Conception and design of the study. DLM and FDP: Acquisition of data. DLM, FCZV: Analysis and interpretation of data. DLM and JLC: First draft manuscript. ALB: Final approval of the version to be submitted.
ISSN:0037-8682
1678-9849
1678-9849
DOI:10.1590/0037-8682-0162-2021