Antibacterial activity and chemical composition of essential oil of Pamburus missionis

• Published in: Journal of ethnopharmacology Vol. 124; no. 1; pp. 151 - 153
• Main Authors: Pavithra, P.S., Sreevidya, N., Verma, Rama S.
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 06-07-2009; Amsterdam; New York: Elsevier; Elsevier
• Subjects: aerial parts; animal pathogenic bacteria; Anti-Bacterial Agents - analysis; Anti-Bacterial Agents - pharmacology; Antibacterial; Antibacterial activity; antibacterial properties; Bacteria - drug effects; bioassays; Biological and medical sciences; dosage; Essential oil; essential oils; Eugenol - analysis; Eugenol - pharmacology; Fatty Alcohols - analysis; Fatty Alcohols - pharmacology; gas chromatography; General pharmacology; mass spectrometry; Medical sciences; medicinal plants; medicinal properties; minimum inhibitory concentration; Monoterpenes - analysis; Monoterpenes - pharmacology; Oils, Volatile - analysis; Oils, Volatile - pharmacology; Palmitic Acid - analysis; Palmitic Acid - pharmacology; Pamburus missionis; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; phytochemicals; Plant Extracts - analysis; Plant Extracts - chemistry; Plant Extracts - pharmacology; Plant Leaves; Rutaceae; Rutaceae - chemistry; Pamburus missionis; Essential oil; Antibacterial; Pharmacognosy; Plant origin; Chemical composition; Antibacterial agent; Medicinal plant
• ISSN: 0378-8741; 1872-7573
• DOI: 10.1016/j.jep.2009.04.016

The aerial parts of Pamburus missionis (Wight) Swingle (Rutaceae) are traditionally used in the treatment of swelling, chronic rheumatism, paralysis, and puerperal diseases.The aim of this work was to investigate the chemical composition and antibacterial activity of essential oil of Pamburus missionis against different bacterial strains.
The essential oil was obtained from fresh leaves by hydro distillation method and its chemical composition was analyzed by GC and GC–MS. The antibacterial activity was determined by disc diffusion and micro broth dilution assay.
GC–MS analysis of the essential oil revealed the presence of 1-tridecanol (38.4%), n-hexadecanoic acid (16.1%), oxygenated monoterpenes (14.4%), monoterpene hydrocarbons (3.1%) and eugenol (1.9%) as the major components. The oil exhibited antibacterial activity at 100 and 450μg against the test organisms with inhibition zones of 7–25mm and minimal inhibitory concentrations values in the range of 10–100 and >100mg/ml.
The present study reveals the antibacterial potency of essential oil of Pamburus missionis. The use of Pamburus missionis in the treatment of various ailments and puerperal diseases can be attributed to its antibacterial property.