Surgery or No Surgery? Exploring the Dilemma of Epistaxis Management in Patients with HHT

• Published in: Journal of clinical medicine Vol. 13; no. 6; p. 1688
• Main Authors: Passali, Giulio Cesare, Santantonio, Mariaconsiglia, Vecchioli, Nadia, Sollazzo, Michela, Rolesi, Rolando, Marotta, Ilenia, Corina, Luigi, Riccioni, Maria Elena, Gaetani, Eleonora, Galli, Jacopo
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 15-03-2024; MDPI
• Subjects: Care and treatment; Compliance; Epistaxis; Estrogens; Genes; Growth factors; Hyaluronic acid; Kinases; Medical research; Medicine, Experimental; Mutation; Nosebleed; Patient compliance; Patients; Pazopanib; Surgery; Surgery, Experimental; Surgical research; Telangiectasia, Hereditary Hemorrhagic; Tranexamic acid; Italy; hereditary hemorrhagic telangiectasia; epistaxis; rhinology
• ISSN: 2077-0383; 2077-0383
• DOI: 10.3390/jcm13061688

: Epistaxis, particularly in Hereditary Hemorrhagic Telangiectasia (HHT) patients, is a common otolaryngological emergency, often requiring complex management. A hierarchy of increasingly invasive interventions, from external compression of the nasal pyramid to nostril closure, is typically proposed and applied.
: We conducted a retrospective study on HHT patients to assess the effectiveness and longevity of invasive procedures postoperatively. Data were collected using the Epistaxis Severity Score (ESS) questionnaire. The primary focus was on changes in the frequency and intensity of epistaxis, while the secondary focus was on the overall quality of life.
: This study found that invasive procedures initially improved the frequency and intensity of epistaxis in HHT patients. However, within 1 to 9 months postoperatively, these benefits often diminished, with hemorrhagic symptoms recurring at similar or worsened levels.
: The findings suggest a need for a cautious and restrained approach to using invasive treatments in managing epistaxis in HHT patients. Highly invasive procedures should be reserved for cases where less invasive methods fail, due to their temporary effectiveness and the risk of causing anatomical-functional changes in the rhino-sinus area, complicating future management of severe epistaxis.