A novel fusion 5′AFF3/3′BCL2 originated from a t(2;18)(q11.2;q21.33) translocation in follicular lymphoma

Follicular lymphoma is the second most frequent type of non-Hodgkin's lymphoma in adults. The basic molecular defect consists of the t(14;18)(q32;q21) translocation, juxtaposing the B-cell lymphoma protein 2 gene BCL2 to the immunoglobulin heavy chain locus IGH@ , and leading to the antiapoptot...

Full description

Saved in:

Bibliographic Details
Published in:	Oncogene Vol. 27; no. 47; pp. 6187 - 6190
Main Authors:	Impera, L, Albano, F, Lo Cunsolo, C, Funes, S, Iuzzolino, P, Laveder, F, Panagopoulos, I, Rocchi, M, Storlazzi, C T
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 16-10-2008 Nature Publishing Group
Subjects:	AFF3 Apoptosis B-cell lymphoma BCL2 Cancer and Oncology Cancer och onkologi Case studies Cell Biology Chromosome 2 Chromosome translocations Chromosomes Clinical Medicine follicular lymphoma fusion gene Fusion protein Genetics Heavy chains Human Genetics Immunoglobulins Immunohistochemistry Internal Medicine Klinisk medicin Lymphocytes B Lymphoma Medical and Health Sciences Medicin och hälsovetenskap Medicine Medicine & Public Health Non-Hodgkin's lymphoma Oncology Proteins short-communication Transcription translocation BCL2 translocation fusion gene follicular lymphoma AFF3
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!