Liver injury associated with dimethyl fumarate in multiple sclerosis patients

Background: In pre-approval trials, there was an increased incidence of mild, transient elevations of liver aminotransferases in study subjects treated with dimethyl fumarate (DMF). Objective/methods: To evaluate post-marketing cases of drug-induced liver injury associated with DMF. Results: We iden...

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Bibliographic Details
Published in:	Multiple sclerosis Vol. 23; no. 14; pp. 1947 - 1949
Main Authors:	Muñoz, Monica A, Kulick, Corrinne G, Kortepeter, Cindy M, Levin, Robert L, Avigan, Mark I
Format:	Journal Article
Language:	English
Published:	London, England SAGE Publications 01-12-2017 Sage Publications Ltd
Subjects:	Adult Bilirubin Bilirubin - blood Chemical and Drug Induced Liver Injury - enzymology Chemical and Drug Induced Liver Injury - etiology Clinical trials Dimethyl Fumarate - adverse effects Female Humans Immunosuppressive Agents - adverse effects Liver Liver diseases Male Medical personnel Middle Aged Multiple sclerosis Multiple Sclerosis - drug therapy Severity of Illness Index Transaminases - blood drug-induced liver injury drug hypersensitivity Dimethyl fumarate multiple sclerosis
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