Effect of chitosan molecular weight on anti-inflammatory activity in the RAW 264.7 macrophage model

Chitosan (300 kDa) was degraded by cellulase to chitosans with molecular weights (MWs) of 156, 72, 7.1, and 3.3 kDa and a chitooligosaccharide mixture (COS). Effects of these on NO secretion, cytokine production, and mitogen-activated protein kinase pathways in lipopolysaccharide (LPS)-induced murin...

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Bibliographic Details

Published in:	International journal of biological macromolecules Vol. 131; pp. 167 - 175
Main Authors:	Chang, Shun-Hsien, Lin, Yi-Yung, Wu, Guan-James, Huang, Chung-Hsiung, Tsai, Guo Jane
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 15-06-2019
Subjects:	Chitosan Cytokines Inflammation Mitogen-activated protein kinase RAW 264.7 macrophages Mitogen-activated protein kinase Inflammation Chitosan RAW 264.7 macrophages Cytokines
Online Access:	Get full text
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