Differential Estrogenic Actions of Endocrine-Disrupting Chemicals Bisphenol A, Bisphenol AF, and Zearalenone through Estrogen Receptor α and β in Vitro

Background: Endocrine-disrupting chemicals (EDCs) are widely found in the environment. Estrogen-like activity is attributed to EDCs, such as bisphenol A (BPA), bisphenol AF (BPAF), and zearalenone (Zea), but mechanisms of action and diversity of effects are poorly understood. Objectives: We used in...

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Bibliographic Details
Published in:	Environmental health perspectives Vol. 120; no. 7; pp. 1029 - 1035
Main Authors:	Li, Yin, Burns, Katherine A., Arao, Yukitomo, Luh, Colin J., Korach, Kenneth S.
Format:	Journal Article
Language:	English
Published:	Research Triangle Park, NC National Institute of Environmental Health Sciences 01-07-2012 US Department of Health and Human Services
Subjects:	Agonists Benzhydryl Compounds Biological and medical sciences Bisphenols Cell Line Cell lines Chemical hazards Endocrine Disruptors - toxicity Environment. Living conditions Estrogen Receptor alpha - metabolism Estrogen Receptor beta - metabolism Estrogen receptors Estrogens HeLa Cells Hep G2 Cells Humans Journalism Medical sciences Phenols - toxicity Plant poisons toxicology Plasmids Public health. Hygiene Public health. Hygiene-occupational medicine Toxicology Vehicles Zearalenone - toxicity Mimetic hormone ERβ ERα Chemical compound Mycotoxin Estrogen Zearalenone Endocrine disruptor BPAF In vitro ERα mutants Toxin Bisphenol A Estrogen receptor α BPA Health and environment ERE
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