Lactate dehydrogenase isoenzymes in human myometrium during pregnancy and labor

Lactate dehydrogenase isoenzymes in human myometrium during pregnancy and labor

Myometrial lactate dehydrogenase isoenzymes were investigated in 32 pregnant women and in 21 women during labor. During pregnancy and labor the H-type LDH isoenzymes were found to preponderate in contrast to M-type LDH isoenzymes. Both H-LDH and M-LDH isoenzyme activities showed a tendency to increa...

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Bibliographic Details
Published in:Acta obstetricia et gynecologica Scandinavica Vol. 61; no. 1; p. 35
Main Authors: Makkonen, M, Puhakainen, E, Hänninen, O, Castrén, O
Format: Journal Article
Language:English
Published: United States 1982
Subjects:
Female
Humans
Hypertension - enzymology
Isoenzymes
L-Lactate Dehydrogenase - metabolism
Labor, Obstetric
Muscles - enzymology
Myometrium - enzymology
Pre-Eclampsia - enzymology
Pregnancy
Pregnancy Complications, Cardiovascular - enzymology
Uterus - enzymology
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Summary:Myometrial lactate dehydrogenase isoenzymes were investigated in 32 pregnant women and in 21 women during labor. During pregnancy and labor the H-type LDH isoenzymes were found to preponderate in contrast to M-type LDH isoenzymes. Both H-LDH and M-LDH isoenzyme activities showed a tendency to increase in normal pregnancy. In severe pre-eclampsia and in chronic hypertension, the uterine M-LDH level decreased. In normal labor, M-LDH activity declined in both the uterine and the rectus abdominis muscles.
ISSN:0001-6349
DOI:10.3109/00016348209156948