A ceramic glazer presenting with extremely high lead levels

A case of lead poisoning in a ceramic glazer is reported. The patient had an extremely high level of blood lead at 29.5 mumol/l, and many of the laboratory features of lead toxicity: normocytic anaemia with marked basophilic stippling, abnormal blood and urinary porphyrins, and elevated liver enzyme...

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Bibliographic Details
Published in:	Human toxicology Vol. 7; no. 2; p. 171
Main Authors:	Ooi, D S, Perkins, S L
Format:	Journal Article
Language:	English
Published:	England 01-03-1988
Subjects:	Adult Calcium - therapeutic use Ceramics Coproporphyrins - analysis Edetic Acid - therapeutic use Female Humans Lead - blood Lead Poisoning - blood Lead Poisoning - diagnosis Lead Poisoning - drug therapy Occupational Diseases - blood Occupational Diseases - diagnosis Occupational Diseases - drug therapy Penicillamine - therapeutic use
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Summary:	A case of lead poisoning in a ceramic glazer is reported. The patient had an extremely high level of blood lead at 29.5 mumol/l, and many of the laboratory features of lead toxicity: normocytic anaemia with marked basophilic stippling, abnormal blood and urinary porphyrins, and elevated liver enzymes. Surprisingly, the patient had no electromyographic evidence of neurologic involvement. The patient was treated with intravenous EDTA-calcium followed by oral penicillamine. Urinary porphyrin and porphyrin precursor excretion followed an interesting pattern, correlating with the chelator used. This patient illustrates that extremely high blood lead level can be achieved through the oral route in an adult.
ISSN:	0144-5952
DOI:	10.1177/096032718800700211