Is ST/HR Slope a Predictor of Coronary Artery Lesion in Effort Angina Pectoris? A Comparison of Exercise Hemodynamic Variables

• Published in: Japanese Heart Journal Vol. 34; no. 4; pp. 385 - 390
• Main Authors: YAMASE, Hiroshi, KAKIMOTO, Tetsuya, FUJITA, Hideki, KIM, Susik, YANO, Takashi, YOKOYAMA, Mitsuhiro
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Tokyo International Heart Journal Association 1993; Japanese Heart Journal Association
• Subjects: Adult; Aged; Angina Pectoris - diagnosis; Angina Pectoris - pathology; Angina Pectoris - physiopathology; Biological and medical sciences; Cardiac Catheterization; Cardiac Output; Cardiology. Vascular system; Coronary heart disease; Coronary Vessels - pathology; Electrocardiography; Exercise Test; Female; Gensini score; Heart; Heart Rate; Hemodynamics; Humans; Invasive exercise test; Male; Medical sciences; Middle Aged; Predictive Value of Tests; Pulmonary capillary pressure; Pulmonary Wedge Pressure; Human; Catheterization; Cardiovascular disease; Angina pectoris; Coronary heart disease; Heart rate; Electrodiagnosis; Right heart; Electrocardiography; Exercise tolerance test; Severity score; Diagnosis; ST depression; Comparative study
• ISSN: 0021-4868; 1348-673X
• DOI: 10.1536/ihj.34.385

This study evaluated the clinical value of the ST/HR slope and exercise hemodynamic variables for the severity of coronary artery lesions. Twenty-nine patients with effort angina pectoris underwent ergometer exercise during right side heart catheterization. The ST/HR slope failed to differentiate three groups stratified by the number of involved coronary vessels. The ST/HR slope was uncorrelated with the Gensini score (r=0.24). By contrast, pulmonary capillary pressure (PCP), cardiac output index (CI) and CI/PCP at peak exercise correlated significantly with the Gensini score (r=0.73, 0.53 and 0.69, respectively). We conclude that the ST/HR slope is not a useful predictor of the severity of coronary artery lesions, while exercise hemodynamic variables measured by right side heart catheter are useful.