Risk factors for acute kidney injury in patients treated with polymyxin B or colistin methanesulfonate sodium

Abstract Polymyxin B (PMB) and colistin, administered as the prodrug colistin methanesulfonate sodium (CMS), are increasingly used to treat carbapenem-resistant Gram-negative bacteria. Nephrotoxicity is the major dose-limiting adverse effect of both polymyxins. A retrospective cohort study of 132 pa...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of antimicrobial agents Vol. 43; no. 4; pp. 349 - 352
Main Authors:	Tuon, Felipe F, Rigatto, Maria Helena, Lopes, Cesar K, Kamei, Letícia K, Rocha, Jaime L, Zavascki, Alexandre P
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-04-2014
Subjects:	Acinetobacter baumannii - drug effects Acinetobacter baumannii - pathogenicity Acinetobacter Infections - drug therapy Acute kidney injury Acute Kidney Injury - chemically induced Acute Kidney Injury - epidemiology Acute Kidney Injury - mortality Acute Kidney Injury Network Acute renal failure Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use Cohort Studies Cohort study Colistin Colistin - adverse effects Colistin - analogs & derivatives Colistin - therapeutic use Creatinine Female Hospital Mortality Humans Infectious Disease Klebsiella Infections - drug therapy Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - pathogenicity Male Middle Aged Polymyxin Polymyxin B - adverse effects Polymyxin B - therapeutic use Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - pathogenicity Pseudomonas Infections - drug therapy Retrospective Studies Risk Factors Vancomycin - adverse effects Vancomycin - therapeutic use Creatinine Acute Kidney Injury Network Colistin Acute kidney injury Cohort study Polymyxin Acute renal failure
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!