Autoantibodies in patients with Down Syndrome: Early senescence of the immune system or precocious markers for immunological diseases?

Aims: Down syndrome (DS) patients present several immunological disturbances, with high rates of infections, malignancies and autoimmune phenomena. The present study aims to evaluate the prevalence of autoantibodies in children and adolescents with DS that are not usually investigated, and to estab...

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Bibliographic Details
Published in:	Journal of paediatrics and child health Vol. 44; no. 4; pp. 182 - 186
Main Authors:	Da Rosa Utiyama, Shirley Ramos, Nisihara, Renato Mitsunori, Nass, Flávia Raphaela, Oliveira, Nanci P, Fiedler, Patrícia T, De Messias-Reason, Iara Taborda
Format:	Journal Article
Language:	English
Published:	Melbourne, Australia Blackwell Publishing Asia 01-04-2008 Blackwell Publishing Ltd
Subjects:	Adolescent Adult Aging, Premature - immunology Autoantibodies - blood Autoantibodies - immunology autoantibody Autoimmune Diseases - blood Autoimmune Diseases - immunology Biomarkers - blood Case-Control Studies Child Child, Preschool Down syndrome Down Syndrome - blood Down Syndrome - immunology Female Humans Immune system Immunology Male Pediatrics Rheumatic diseases rheumatoid factor Rheumatoid Factor - blood Rheumatoid Factor - immunology
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