Multilayer chromosome organization through DNA bending, bridging and extrusion

Highlights • Bacterial nucleoids are compact, dynamic and highly organized structures. • Abundant DNA bending proteins cause local folding of chromosomal DNA. • DNA bridging proteins organize large parts of chromosomes into isolated domains. • DNA extruder actively relocate and position DNA sequence...

Full description

Saved in:

Bibliographic Details
Published in:	Current opinion in microbiology Vol. 22; pp. 102 - 110
Main Author:	Gruber, Stephan
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-12-2014
Subjects:	Bacterial Proteins - chemistry Bacterial Proteins - metabolism Chromosomes - genetics Chromosomes - metabolism DNA - chemistry DNA - genetics DNA - metabolism DNA-Binding Proteins - chemistry DNA-Binding Proteins - metabolism Genome, Bacterial Pathology Protein Binding
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Highlights • Bacterial nucleoids are compact, dynamic and highly organized structures. • Abundant DNA bending proteins cause local folding of chromosomal DNA. • DNA bridging proteins organize large parts of chromosomes into isolated domains. • DNA extruder actively relocate and position DNA sequences within a cell. • Models for the action of SMC protein complexes are considered.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	1369-5274 1879-0364
DOI:	10.1016/j.mib.2014.09.018