Association of bGH and Pit-1 gene variants with milk production traits in dairy Gyr bulls

The objective of this study was to obtain genetic marker information in the Gyr breed by analyzing bGH and Pit-1 gene polymorphisms and to verify their association with milk production traits. One sample including 40 Gyr bulls were genotyped at two bGH gene restriction sites (bGH- AluI and bGH-MspI)...

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Published in:Pesquisa agropecuaria brasileira Vol. 39; no. 2; pp. 147 - 150
Main Authors: Mattos, Keiko Kusamura de(Universidade Federal de São Carlos Dep. de Genética e Evolução), Del Lama, Silvia Nassif(Universidade Federal de São Carlos Dep. de Genética e Evolução), Martinez, Mario Luiz(Embrapa Gado de Leite), Freitas, Ary Ferreira(Embrapa Gado de Leite)
Format: Journal Article
Language:English
Published: Embrapa Informação TecnológicaPesquisa Agropecuária Brasileira 01-02-2004
Embrapa Secretaria de Pesquisa e Desenvolvimento; Pesquisa Agropecuária Brasileira
Embrapa Informação Tecnológica
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Abstract The objective of this study was to obtain genetic marker information in the Gyr breed by analyzing bGH and Pit-1 gene polymorphisms and to verify their association with milk production traits. One sample including 40 Gyr bulls were genotyped at two bGH gene restriction sites (bGH- AluI and bGH-MspI) and at one restriction site in the Pit-1 gene (Pit-1 HinfI). The bGH-MspI(-) allele was favorable for fat milk percentage. The heterozigous Pit-1 HinfI (+/-) bulls were superior for fat milk production, in relation to homozigous Pit-1 HinfI (+/+). The Pit-1 and bGH genes are strong candidates in the dairy cattle QTL search, and zebuine populations are promising samples for this purpose. O objetivo deste estudo foi obter informações dos marcadores genéticos na raça Gir pela análise dos polimorfismos nos genes bGH e Pit-1, e verificar suas associações com características de produção leiteira. Uma amostra de 40 touros da raça Gir foi genotipada, nos dois sítios de restrição no gene bGH (bGH-AluI e bGH-MspI) e em um sítio de restrição no gene Pit-1 (Pit-1 HinfI). O alelo bGH-MspI(-) favoreceu a porcentagem de gordura no leite. Os touros heterozigotos Pit-1 HinfI (+/-) foram superiores quanto à produção de gordura no leite, em relação aos homozigotos Pit-1 HinfI (+/+). Os genes Pit-1 e bGH são fortes candidatos à pesquisa de QTLs em raças leiteiras e populações zebuínas representam uma amostra promissora para esse propósito.
AbstractList The objective of this study was to obtain genetic marker information in the Gyr breed by analyzing bGH and Pit-1 gene polymorphisms and to verify their association with milk production traits. One sample including 40 Gyr bulls were genotyped at two bGH gene restriction sites (bGH- AluI and bGH-MspI) and at one restriction site in the Pit-1 gene (Pit-1 HinfI). The bGH-MspI(-) allele was favorable for fat milk percentage. The heterozigous Pit-1 HinfI (+/-) bulls were superior for fat milk production, in relation to homozigous Pit-1 HinfI (+/+). The Pit-1 and bGH genes are strong candidates in the dairy cattle QTL search, and zebuine populations are promising samples for this purpose.
The objective of this study was to obtain genetic marker information in the Gyr breed by analyzing bGH and Pit-1 gene polymorphisms and to verify their association with milk production traits. One sample including 40 Gyr bulls were genotyped at two bGH gene restriction sites (bGH- AluI and bGH-MspI) and at one restriction site in the Pit-1 gene (Pit-1 HinfI). The bGH-MspI(-) allele was favorable for fat milk percentage. The heterozigous Pit-1 HinfI (+/-) bulls were superior for fat milk production, in relation to homozigous Pit-1 HinfI (+/+). The Pit-1 and bGH genes are strong candidates in the dairy cattle QTL search, and zebuine populations are promising samples for this purpose. O objetivo deste estudo foi obter informações dos marcadores genéticos na raça Gir pela análise dos polimorfismos nos genes bGH e Pit-1, e verificar suas associações com características de produção leiteira. Uma amostra de 40 touros da raça Gir foi genotipada, nos dois sítios de restrição no gene bGH (bGH-AluI e bGH-MspI) e em um sítio de restrição no gene Pit-1 (Pit-1 HinfI). O alelo bGH-MspI(-) favoreceu a porcentagem de gordura no leite. Os touros heterozigotos Pit-1 HinfI (+/-) foram superiores quanto à produção de gordura no leite, em relação aos homozigotos Pit-1 HinfI (+/+). Os genes Pit-1 e bGH são fortes candidatos à pesquisa de QTLs em raças leiteiras e populações zebuínas representam uma amostra promissora para esse propósito.
Author Del Lama, Silvia Nassif(Universidade Federal de São Carlos Dep. de Genética e Evolução)
Mattos, Keiko Kusamura de(Universidade Federal de São Carlos Dep. de Genética e Evolução)
Freitas, Ary Ferreira(Embrapa Gado de Leite)
Martinez, Mario Luiz(Embrapa Gado de Leite)
AuthorAffiliation Embrapa Gado de Leite
Universidade Federal de São Carlos
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  fullname: Martinez, Mario Luiz(Embrapa Gado de Leite)
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  fullname: Freitas, Ary Ferreira(Embrapa Gado de Leite)
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Cites_doi 10.1152/physrev.1998.78.3.745
10.3168/jds.S0022-0302(97)76319-7
10.1111/j.1365-2052.1995.tb02620.x
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Issue 2
Keywords dairy cattle
polimorfismo
zebu
gado leiteiro
polymorphism
marcador genético
genetic markers
Language English
License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. http://creativecommons.org/licenses/by-nc/4.0
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Snippet The objective of this study was to obtain genetic marker information in the Gyr breed by analyzing bGH and Pit-1 gene polymorphisms and to verify their...
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SubjectTerms AGRICULTURE, DAIRY & ANIMAL SCIENCE
AGRICULTURE, MULTIDISCIPLINARY
dairy cattle
gado leiteiro
genetic markers
marcador genético
polimorfismo
polymorphism
zebu
Title Association of bGH and Pit-1 gene variants with milk production traits in dairy Gyr bulls
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