Hereditary Spastic Paraplegia and Intellectual Disability: Clinicogenetic Lessons From a Family Suggesting a Dual Genetics Diagnosis

Hereditary spastic paraplegias (HSPs) are a heterogeneous group of genetic disorders with spastic paraparesis as the main clinical feature. Complex forms may co-occur with other motor, sensory, and cognitive impairment. A growing number of loci and genes are being identified, but still more than 50%...

Full description

Bibliographic Details

Published in:	Frontiers in neurology Vol. 11; p. 41
Main Authors:	Aguilera-Albesa, Sergio, de la Hoz, Ana Belén, Ibarluzea, Nekane, Ordóñez-Castillo, Andrés R, Busto-Crespo, Olivia, Villate, Olatz, Ibiricu-Yanguas, María Asunción, Yoldi-Petri, María E, García de Gurtubay, Iñaki, Perez de Nanclares, Guiomar, Pereda, Arrate, Tejada, María Isabel
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 14-02-2020
Subjects:	copy number variants dual genetic etiology hereditary spastic paraplegia intellectual disability Neurology SPG 31 copy number variants hereditary spastic paraplegia SPG 31 intellectual disability dual genetic etiology
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!