Individual capacity differences predict working memory performance and prefrontal activity following dopamine receptor stimulation

Dopamine receptors are abundant in the prefrontal cortex (PFC), a critical region involved in working memory. This pharmacological fMRI study tested the relationships between dopamine, PFC function, and individual differences in working memory capacity. Subjects performed a verbal delayed-recognitio...

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Bibliographic Details
Published in:	Cognitive, affective, & behavioral neuroscience Vol. 5; no. 2; pp. 212 - 221
Main Authors:	Gibbs, Sasha E B, D'Esposito, Mark
Format:	Journal Article
Language:	English
Published:	United States Springer Nature B.V 01-06-2005
Subjects:	Adult Amphetamines Analysis of Variance Arousal - drug effects Bromocriptine - pharmacology Cues Dopamine Dopamine Agonists - pharmacology Double-Blind Method Drug dosages Female Humans Image Processing, Computer-Assisted - methods Individuality Magnetic Resonance Imaging - methods Male Memory Memory, Short-Term - drug effects Memory, Short-Term - physiology Monkeys & apes Motor Activity - drug effects Neuropsychological Tests - statistics & numerical data Predictive Value of Tests Prefrontal Cortex - blood supply Prefrontal Cortex - drug effects Prefrontal Cortex - physiology Reaction Time - drug effects Signal to noise ratio Statistics as Topic Time Factors
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