Application of cinnamoyl derivative as a new ligand for dispersive liquid-liquid microextraction and spectrophotometric determination of cobalt

• Published in: Journal of analytical chemistry (New York, N.Y.) Vol. 70; no. 3; pp. 298 - 304
• Main Authors: Elečková, L., Balogh, I. S., Imrich, J., Andruch, V.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01-03-2015; Springer
• Subjects: Analytical Chemistry; Chemical properties; Chemistry; Chemistry and Materials Science; Cobalt; Extraction (Chemistry); Laws, regulations and rules; Methods; Toluene; Hungary; Slovakia; cobalt determination; vitamin B12; cinnamoyl pyrones; UV-Vis detection; dispersive liquid-liquid microextraction
• ISSN: 1061-9348; 1608-3199
• DOI: 10.1134/S1061934815030053

The method is based on the reaction of Co(II) with 3-[4-(dimethylamino)cinnamoyl]-4-hydroxy-6-methyl-2H-pyran-2-one (ligand) and a dimethylindocarbocyanine dye, followed by dispersive liquid-liquid microextraction of the ion associate formed and subsequent spectrophotometric detection. The appropriate experimental conditions were found to be: pH 9, 0.14 mM dye, toluene (extraction solvent) containing 2.25 mM of ligand, acetonitrile (dispersive solvent) and carbon tetrachloride (auxiliary solvent). Beer’s law is obeyed in the range 0.06–0.42 mg/L of Co(II) at a wavelength of 558 nm. The limit of detection, calculated as three times the standard deviation of the blank test (
n
= 10), was found to be 9 μg/L for Co(II). The method was applied to the determination of cobalt in spiked water samples and a vitamin B12 pharmaceutical injection.