Aortic thrombosis in a dog with chronic lymphocytic leukemia

• Published in: Ciência rural Vol. 50; no. 4
• Main Authors: Ripplinger, Angel, Silva, Ana Paula da, Wrzesinski, Mathias Reginatto, Ferrarin, Dênis Antonio, Schwab, Marcelo Luís, Pozzobon, Ricardo, Flores, Mariana Martins, Thompson, Ruth Pamela, Mario, Fabiana, Mazzanti, Alexandre
• Format: Journal Article
• Language: English
• Published: Santa Maria Universidade Federal de Santa Maria Centro de Ciencias Rurais 01-01-2020; Universidade Federal de Santa Maria
• Subjects: AGRONOMY; Antibodies; Aorta; Blood clots; Bone marrow; canine; Chronic lymphocytic leukemia; Coronary vessels; Creatinine; Diagnosis; Dogs; ischemic neuromyopathy; Kidneys; Leukemia; Lymphatic leukemia; Lymphocytes; lymphoid leukemia; Mental disorders; Necropsy; Neoplasms; Spinal cord; Spleen; Thromboembolism; Thrombosis; thrombus; Tumors; Ultrasonic imaging; Ultrasound; Veins & arteries; leucemia linfoide; trombo; lymphoid leukemia; caninos; canine; neuromiopatia isquêmica; thrombus; ischemic neuromyopathy
• ISSN: 0103-8478; 1678-4596; 1678-4596
• DOI: 10.1590/0103-8478cr20190719

The aim of this report was to describe a case of aortic thrombosis (AT) secondary to chronic lymphocytic leukemia (CLL). Although, different types of neoplasms are described as possible causes of aortic thrombosis, CLL was not yet considered. The dog showed signs of lameness that worsened with exercise. The diagnosis of AT was made by ultrasound examination. The diagnosis of CLL was made by necropsy, which showed the presence of small lymphocytes with the appearance of mature lymphocytes in the bone marrow, spleen, liver and kidneys. The importance of including CLL in the possible causes of AT in dogs, in addition to the suspicion of AT in cases of neuromuscular disease, was highlighted.
RESUMO: O objetivo do presente relato é descrever um caso de trombose aórtica (AT) secundária a leucemia linfocítica crônica (LLC). Embora diferentes tipos de neoplasmas sejam descritos como possíveis causas de trombose aórtica, a LLC ainda não foi considerada. O cão mostrou sinais de claudicação que pioravam com o exercício. O diagnóstico de AT foi realizado por exame ultrassonográfico. O diagnóstico de LLC foi feito por necropsia, que mostrou a presença de pequenos linfócitos com aparência de linfócitos maduros na medula óssea, baço, fígado e rins. Destaca-se a importância da inclusão da LLC nas possíveis causas de AT em cães, além da suspeita de AT em casos de doença neuromuscular.