Understanding the Omicron Variant Impact in Healthcare Workers: Insights from the Prospective COVID-19 Post-Immunization Serological Cohort in Munich (KoCo-Impf) on Risk Factors for Breakthrough and Reinfections

This study analyzes immune responses to SARS-CoV-2 vaccination and infection, including asymptomatic cases, focusing on infection risks during the Omicron wave, particularly among high-risk healthcare workers. In the KoCo-Impf study, we monitored 6088 vaccinated participants in Munich aged 18 and ab...

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Bibliographic Details
Published in:	Viruses Vol. 16; no. 10; p. 1556
Main Authors:	Janke, Christian, Rubio-Acero, Raquel, Weigert, Maximilian, Reinkemeyer, Christina, Khazaei, Yeganeh, Kleinlein, Lisa, Le Gleut, Ronan, Radon, Katja, Hannes, Marlene, Picasso, Francesco, Lucke, Anne Elisabeth, Plank, Michael, Kotta, Irene Charlotte, Paunovic, Ivana, Zhelyazkova, Ana, Noreña, Ivan, Winter, Simon, Hoelscher, Michael, Wieser, Andreas, Küchenhoff, Helmut, Castelletti, Noemi, On Behalf Of The Orchestra Working Group
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 30-09-2024 MDPI
Subjects:	Adolescent Adult Aged Antibodies Antibodies, Viral - blood Antibodies, Viral - immunology Breakthrough Infections COVID-19 COVID-19 - epidemiology COVID-19 - immunology COVID-19 vaccines COVID-19 Vaccines - administration & dosage COVID-19 Vaccines - immunology Disease transmission Female Germany - epidemiology Health aspects Health care health care workers Health Personnel Humans Immune response immunologic response Infectious diseases Male Medical personnel Middle Aged Nosocomial infections Nucleocapsids Pandemics Personal protective equipment Prospective Studies Regression analysis Reinfection - epidemiology Reinfection - immunology Reinfection - virology Risk Factors SARS-CoV-2 SARS-CoV-2 - immunology Seroepidemiologic Studies Serology Severe acute respiratory syndrome coronavirus 2 Vaccination Viral infections Young Adult Germany COVID-19 immunologic response SARS-CoV-2 breakthrough infections seroprevalence antibodies health care workers ORCHESTRA reinfections vaccination
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