Association of mannose-binding lectin gene polymorphisms with the development of pulmonary tuberculosis in China

Mannose-binding lectin (MBL) is an important protein in the lectin pathway of the immune system. This study explores the association between MBL polymorphism and the susceptibility to tuberculosis (TB). The association between the MBL2 polymorphisms and serum MBL levels is also analyzed in the prese...

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Bibliographic Details
Published in:	BMC infectious diseases Vol. 17; no. 1; p. 210
Main Authors:	Guo, Yan-Ling, Liu, Yang, Ban, Wu-Juan, Sun, Qi, Shi, Guang-Li
Format:	Journal Article
Language:	English
Published:	England BioMed Central 15-03-2017
Subjects:	Adult Aged Aged, 80 and over Binding Blood Case-Control Studies China - epidemiology Codons Demographics Deoxyribonucleic acid Disease DNA Drug resistance Enzyme-linked immunosorbent assay Enzymes Female Gene polymorphism Genetic Predisposition to Disease - genetics Genotype Humans Immune system Infections Infectious diseases Lectins Male Mannose Mannose-binding lectin Mannose-Binding Lectin - genetics Middle Aged Patients Polymerase chain reaction Polymorphism Polymorphism, Genetic Population Proteins Restriction fragment length polymorphism Sample size Studies Tuberculosis Tuberculosis, Pulmonary - epidemiology Tuberculosis, Pulmonary - genetics Tuberculosis, Pulmonary - immunology Tuberculosis, Pulmonary - physiopathology Variance analysis Young Adult United States > US Mannose-binding lectin (MBL) Tuberculosis Susceptibility Polymorphism
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