Use of all-trans retinoic acid to treat acute promyelocytic leukemia: A case with very severe features at the onset in Nicaragua

We observed a child with acute promyelocytic leukemia (APL) who, at the onset, had extremely severe hemorrhagic and septic complications. According to our experience in Nicaragua, there was a very high risk of early death. The patient was successfully treated with a program that included all‐trans r...

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Bibliographic Details
Published in:	Medical and pediatric oncology Vol. 26; no. 4; pp. 258 - 260
Main Authors:	Flores, A., Malta, A., Pacheco, C., Baez, F., Ocampo, E., Conter, V., Masera, G., Biondi, A., Rovelli, A.
Format:	Journal Article
Language:	English
Published:	New York Wiley Subscription Services, Inc., A Wiley Company 01-04-1996 Wiley-Liss
Subjects:	acute promyelocytic leukemia all-trans-retinoic acid Antineoplastic agents Antineoplastic Agents - administration & dosage Antineoplastic Agents - economics Antineoplastic Agents - therapeutic use Bacteremia - microbiology Biological and medical sciences Chemotherapy Child childhood Developing Countries Drug Costs Female Hemorrhage - etiology Humans Leukemia, Promyelocytic, Acute - drug therapy Medical sciences Nicaragua Pharmacology. Drug treatments Pseudomonas aeruginosa Pseudomonas Infections Remission Induction Skin Diseases, Bacterial - etiology Staphylococcal Skin Infections Tretinoin - administration & dosage Tretinoin - economics Tretinoin - therapeutic use Nicaragua Human Antineoplastic agent Case study Promyelocytic leukemia Drug combination Treatment Acute Female Malignant hemopathy Child Retinoic acid
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