Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post‐brain metastases survival

BACKGROUND: Melanoma patients who develop brain metastases (B‐Met) have limited survival and are excluded from most clinical trials. In the current study, the authors attempted to identify primary tumor characteristics and clinical features predictive of B‐Met development and post‐B–Met survival. ME...

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Bibliographic Details
Published in:	Cancer Vol. 117; no. 8; pp. 1711 - 1720
Main Authors:	Zakrzewski, Jan, Geraghty, Laurel N., Rose, Amy E., Christos, Paul J., Mazumdar, Madhu, Polsky, David, Shapiro, Richard, Berman, Russell, Darvishian, Farbod, Hernando, Eva, Pavlick, Anna, Osman, Iman
Format:	Journal Article
Language:	English
Published:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 15-04-2011 Wiley-Blackwell
Subjects:	Age Factors Aged Biological and medical sciences Brain Brain Neoplasms - mortality Brain Neoplasms - pathology Brain Neoplasms - secondary Cancer Clinical trials Dermatology Female Head and neck Humans Male Medical sciences Melanoma Melanoma - mortality Melanoma - pathology Melanoma - secondary Metastases Middle Aged Multivariate analysis outcomes Prognosis Regression analysis Skin Neoplasms - pathology Survival Survival Analysis Tumors Tumors of the skin and soft tissue. Premalignant lesions ulceration Nervous system diseases Prognosis Brain cancer Central nervous system melanoma Tumorigenicity Malignant tumor Cerebral metastasis brain Carcinogenesis Survival Cerebral disorder Encephalon metastases Cancerology outcomes Central nervous system disease Malignant melanoma Primary Ulceration Cancer
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