Polybutylene Succinate (PBS) - Polycaprolactone (PCL) Blends Compatibilized with Poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (PEO-PPO-PEO) Copolymer for Biomaterial Applications

• Published in: Polymer-plastics technology and engineering Vol. 53; no. 11; pp. 1178 - 1193
• Main Authors: Can, Erde, Bucak, Seyda, Kınacı, Emre, Çalıkoğlu, Ayşe Ceren, Köse, Gamze Torun
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Taylor & Francis Group 05-08-2014; Taylor & Francis; Taylor & Francis Ltd
• Subjects: Applied sciences; Biocompatibility; Biological and medical sciences; Biomaterial; Biomaterials; Biomedical materials; Blends; Block copolymers; Buffer solutions; Compatibility; Compatibilizer; Compatibilizers; Copolymers; Cytotoxicity; Dynamic mechanical analysis; Ethylene oxide; Exact sciences and technology; Machinery and processing; Medical sciences; Melt blends; Moulding compound preparation. Mixing; PBS; PCL; Plastics; Polybutylenes; Polycaprolactone; Polyethylene oxide; Polymer blend; Polymer blends; Polymer industry, paints, wood; Propylene oxide; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgical implants; Technology of polymers; Technology. Biomaterials. Equipments; Thermomechanical analysis; Thermomechanical properties; Toxicity testing; Cell proliferation; Biological properties; Mixing; Polymer blend; Property composition relationship; Cytotoxicity; Compatibilizer; Lactone polymer; Heterogeneous mixture; Structure composition relationship; Cyclic ether copolymer; Aliphatic polymer; Biocompatibility; Biomaterial; Propylene oxide copolymer; Polysuccinate; Chemical properties; Polycaprolactone; PBS; Polymer blends; Ester polymer; Crystallinity; Ethylene oxide copolymer; Experimental study; Thermal properties; Hydrolysis resistance; Dynamic mechanical properties; Morphology; PCL; Block copolymer
• ISSN: 0360-2559; 1525-6111
• DOI: 10.1080/03602559.2014.886119

This study reports the preparation and characterization of Polybutylene Succinate (PBS)-Polycaprolactone (PCL) melt blends (10-40 wt.% PCL) in the presence of a compatibilizer, in order to explore their potential use as a biomaterial. The thermal transitions, as well as the crystallinity of the polymer blends were analyzed by Differential Scanning Calorimetry, the thermomechanical properties were analyzed via Dynamic Mechanical Analysis and phase morphologies were characterized by Scanning Electron Microscopy. Degradation profiles of the blends were analyzed in PBS buffer solution at pH 7.4 at 37°C via pH measurements. Cytotoxicity of the PBS/PCL films were tested by MTS assay.