New intragastric sleeve technique reduces adipose tissue in pig experimental model: tomographic study

• Published in: Scientific reports Vol. 10; no. 1; p. 18122
• Main Authors: da Silva Ribeiro, Mariana, Paiva Araújo dos Scheiba Zorron, Ricardo, Quina Silva, Saulo José, Ruiz Cadena, Silvia Marcela, Borges dos Santos Junior, Marcelo, Antunes, Fernanda, de Souza Vieira, Guilherme, Quirino, Celia Raquel, Lacerda de Abreu Oliveira, André
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22-10-2020; Nature Publishing Group
• Subjects: 692/4020/2741/533; 692/699/2743/393; Adipose tissue; Adipose Tissue - growth & development; Adipose Tissue - metabolism; Animals; Bariatric Surgery - methods; Body weight; Body weight gain; Correlation coefficient; Gastrectomy; Gastrointestinal surgery; Humanities and Social Sciences; Laparoscopy; Models, Animal; multidisciplinary; Obesity, Morbid - pathology; Obesity, Morbid - surgery; Reconstructive Surgical Procedures - methods; Science; Science (multidisciplinary); Stomach - pathology; Stomach - surgery; Surgery; Swine; Tomography, X-Ray Computed; Weight Loss
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-020-74846-8

In order to implement a new bariatric surgery technique, we verify the efficacy of intragastric sleeve to reduce weight gain and subcutaneous adipose tissue (SAT). Animals were divided into two groups: G1 (single-port intragastric sleeve) and G2 (sham group). The stomach was surgically reduced by single-port intragastric sutures to fo a gastric sleeve. Animals were submitted to computer tomography (CT) before the surgical procedure and after 18 weeks. Images were analyzed and measurements of the thickness of SAT, depth and width of the
longissimus dorsi
muscle and the rib eye area were made. Body weight and CT measurements were analyzed using the GLM PROC. The correlation coefficients were calculated among weight, moments and measures. There was a significant difference in weight gain, in which G1 had an average of 42.803 ± 3.206 kg, lower than G2 (45.966 ± 4.767 kg). The mean values for SAT and muscle measurements differed significantly between groups, in which G1 achieved the lowest values. All variables had significant correlations and high magnitude. Intragastric
sleeve
surgery induced a significant decrease of SAT. The new intragastric
sleeve
technique is feasible, safe and effective, mainly in reducing fat deposition, making it an important alternative in bariatric surgical treatment.