Daridorexant, a New Dual Orexin Receptor Antagonist to Treat Insomnia Disorder

Objective To evaluate the dose–response relationship of daridorexant, a new dual orexin receptor antagonist, on sleep variables in subjects with insomnia disorder. Methods Adults (≤64 years) with insomnia disorder were randomized (1:1:1:1:1:1) to receive daily oral placebo, daridorexant (5, 10, 25,...

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