Is experience of the HIV/AIDS epidemic associated with responses to COVID-19? Evidence from the Rural Malawi

• Published in: PloS one Vol. 18; no. 10; p. e0292378
• Main Authors: Anglewicz, Philip, Lamba, Sneha, Kohler, Iliana, Mwera, James, Zulu, Andrew, Kohler, Hans-Peter
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 25-10-2023; Public Library of Science (PLoS)
• Subjects: Acquired Immunodeficiency Syndrome - epidemiology; Acquired Immunodeficiency Syndrome - prevention & control; COVID-19 - epidemiology; HIV Infections - epidemiology; HIV Infections - prevention & control; Humans; Longitudinal Studies; Malawi - epidemiology; Medicine and Health Sciences; Pandemics; People and Places; Malawi
• DOI: 10.1371/journal.pone.0292378
• EISSN: 1932-6203

Starting in late 2019, the coronavirus "SARS-CoV-2", which causes the disease Covid-19, spread rapidly and extensively. Although many have speculated that prior experience with infectious diseases like HIV/AIDS, Ebola, or SARS would better prepare populations in sub-Saharan Africa for COVID-19, this has not been formally tested, primarily due to data limitations.
We use longitudinal panel data from the Malawi Longitudinal Study of Families and Health (MLSFH, waves 2006, 2008, and 2020) to examine the association between exposure to the HIV/AIDS epidemic and perceptions of, and behavioral response to, the COVID-19 pandemic. We measured exposure to HIV infection through perceived prevalence of HIV/AIDS in the community, worry about HIV infection, perceived likelihood of HIV infection, and actual HIV status; and the experience of HIV/AIDS-related mortality through self-reports of knowing members of the community and extended family who died from AIDS (measured in 2006 or 2008). Our outcome measures were perceptions of COVID-19 presence in the community, perceptions of individual vulnerability to COVID-19, and prevention strategies to avoid COVID-19 collected through phone-interviews in 2020.
Based on our data analysis using multivariable regression models, we found that the experience of HIV-related mortality was positively associated with perceptions of COVID-19 prevalence in the community and preventive behaviors for COVID-19. However, perceived vulnerability to HIV-AIDS infection and actual HIV positive status 10-years prior to the COVID-19 pandemic are generally not associated with COVID-19 perceptions and behaviors.
Our results suggest that COVID-19-related behaviors are impacted more by experience of AIDS mortality instead of HIV/AIDS risk perceptions, and that individuals may be correctly viewing HIV/AIDS and COVID-19 transmission as distinct disease processes.