Borrowing Hydrogen in the Activation of Alcohols
Alcohols can be temporarily converted into carbonyl compounds by the metal‐catalysed removal of hydrogen. The carbonyl compounds are reactive in a wider range of transformations than the precursor alcohols and can react in situ to give imines, alkenes, and α‐functionalised carbonyl compounds. The me...
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Published in: | Advanced synthesis & catalysis Vol. 349; no. 10; pp. 1555 - 1575 |
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Main Authors: | , , |
Format: | Journal Article |
Language: | English |
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WILEY-VCH Verlag
02-07-2007
WILEY‐VCH Verlag |
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Abstract | Alcohols can be temporarily converted into carbonyl compounds by the metal‐catalysed removal of hydrogen. The carbonyl compounds are reactive in a wider range of transformations than the precursor alcohols and can react in situ to give imines, alkenes, and α‐functionalised carbonyl compounds. The metal catalyst, which had borrowed the hydrogen, then returns it to the transformed carbonyl compound, leading to an overall process in which alcohols can be converted into amines, compounds containing CC bonds and β‐functionalised alcohols. |
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AbstractList | Alcohols can be temporarily converted into carbonyl compounds by the metal‐catalysed removal of hydrogen. The carbonyl compounds are reactive in a wider range of transformations than the precursor alcohols and can react
in situ
to give imines, alkenes, and α‐functionalised carbonyl compounds. The metal catalyst, which had borrowed the hydrogen, then returns it to the transformed carbonyl compound, leading to an overall process in which alcohols can be converted into amines, compounds containing CC bonds and β‐functionalised alcohols. Alcohols can be temporarily converted into carbonyl compounds by the metal‐catalysed removal of hydrogen. The carbonyl compounds are reactive in a wider range of transformations than the precursor alcohols and can react in situ to give imines, alkenes, and α‐functionalised carbonyl compounds. The metal catalyst, which had borrowed the hydrogen, then returns it to the transformed carbonyl compound, leading to an overall process in which alcohols can be converted into amines, compounds containing CC bonds and β‐functionalised alcohols. Alcohols can be temporarily converted into carbonyl compounds by the metal-catalysed removal of hydrogen. The carbonyl compounds are reactive in a wider range of transformations than the precursor alcohols and can react in situ to give imines, alkenes, and -functionalised carbonyl compounds. The metal catalyst, which had borrowed the hydrogen, then returns it to the transformed carbonyl compound, leading to an overall process in which alcohols can be converted into amines, compounds containing CC bonds and -functionalised alcohols. . |
Author | Hamid, Malai Haniti S. A. Slatford, Paul A. Williams, Jonathan M. J. |
Author_xml | – sequence: 1 givenname: Malai Haniti S. A. surname: Hamid fullname: Hamid, Malai Haniti S. A. organization: Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, U.K. Fax: (+ 44)-1225-386-231 – sequence: 2 givenname: Paul A. surname: Slatford fullname: Slatford, Paul A. organization: Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, U.K. Fax: (+ 44)-1225-386-231 – sequence: 3 givenname: Jonathan M. J. surname: Williams fullname: Williams, Jonathan M. J. email: j.m.j.williams@bath.ac.uk organization: Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, U.K. Fax: (+ 44)-1225-386-231 |
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Snippet | Alcohols can be temporarily converted into carbonyl compounds by the metal‐catalysed removal of hydrogen. The carbonyl compounds are reactive in a wider range... Alcohols can be temporarily converted into carbonyl compounds by the metal-catalysed removal of hydrogen. The carbonyl compounds are reactive in a wider range... |
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SubjectTerms | alcohols amines catalysis transfer hydrogenation transition metals |
Title | Borrowing Hydrogen in the Activation of Alcohols |
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