Porcine lymphotropic herpesvirus DNA detection in multiple organs of pigs in Brazil

• Published in: Brazilian journal of microbiology Vol. 51; no. 4; pp. 2145 - 2152
• Main Authors: Dall Agnol, Alais M., Leme, Raquel A., Suphoronski, Suelen A., Oliveira, Thalita E. S., Possatti, Flávia, Saporiti, Viviane, Headley, Selwyn A., Alfieri, Amauri Alcindo, Alfieri, Alice Fernandes
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01-12-2020
• Subjects: Biomedical and Life Sciences; Food Microbiology; Life Sciences; Medical Microbiology; Microbial Ecology; Microbial Genetics and Genomics; Microbiology; Mycology; Veterinary Microbiology - Short Communication; Swine; Suid gammaherpesvirus; Pan-herpesvirus; PLHV
• ISSN: 1517-8382; 1678-4405
• DOI: 10.1007/s42770-020-00335-9

We investigated the porcine lymphotropic herpesvirus (PLHV) DNA presence in multiple organs of pigs. Biological samples (
n
 = 136) included tissue fragments of the central nervous system, heart, kidney, liver, lungs, spleen, urinary bladder, and urine. Sixty-eight (50%) organs were PLHV DNA-positive. None of the urine samples were detected with the virus genome. Although the presence of the PLHV DNA in the urinary bladder and kidney has been detected, it was not possible to show whether urine can be considered an effective route of virus shedding. This study warns to the risk of PLHV zoonotic transmission by xenotransplantation of tissues of porcine origin.