Amphetamine Induces Oxidative Stress, Glial Activation and Transient Angiogenesis in Prefrontal Cortex via AT1-R

Background: Amphetamine (AMPH) alters neurons, glia and microvessels, which affects neurovascular unit coupling, leading to disruption in brain functions such as attention and working memory. Oxidative stress plays a crucial role in these alterations. The angiotensin type I receptors (AT 1 -R) media...

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Bibliographic Details

Published in:	Frontiers in pharmacology Vol. 12; p. 647747
Main Authors:	Basmadjian, Osvaldo M., Occhieppo, Victoria B., Marchese, Natalia A., Silvero C., M. Jazmin, Becerra, María Cecilia, Baiardi, Gustavo, Bregonzio, Claudia
Format:	Journal Article
Language:	English
Published:	Frontiers Media S.A 03-05-2021
Subjects:	amphetamine angiogeneis AT1 receptor glia oxidative stress Pharmacology working memory
Online Access:	Get full text
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