High-density polyethylene facial implants show surface oxidation in SEM and EDX examination: A pilot study

Previous histopathological studies on explanted Medpor high-density polyethylene (HDPE) facial implants indicated signs of material destruction and claimed to observe phagocytized HDPE particles within the tissue samples beside the usual type IV reaction with severe fibrosis. We examined new and exp...

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Published in:	Acta biomaterialia Vol. 5; no. 4; pp. 1158 - 1162
Main Authors:	Draenert, G.F., Doeblinger, M., Draenert, M., Gosau, M.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-05-2009
Subjects:	Biocorrosion Chemistry Techniques, Analytical Implant Microscopy, Electron, Scanning Oxidation Oxidation-Reduction Pilot Projects Polyethylene Polyethylene - chemistry Prostheses and Implants - ultrastructure Surface Properties X-Rays Polyethylene Oxidation Implant Biocorrosion
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Abstract	Previous histopathological studies on explanted Medpor high-density polyethylene (HDPE) facial implants indicated signs of material destruction and claimed to observe phagocytized HDPE particles within the tissue samples beside the usual type IV reaction with severe fibrosis. We examined new and explanted Medpor material with scanning electron microscopy (SEM) and energy-dispersive X-ray analysis (EDX). The implant surface of three patient-derived specimens showed significantly higher oxygenation in EDX analysis and morphological changes in SEM compared to the new unused material directly after opening of the package and after 1 year of exposure to air. Our preliminary findings indicate a possible oxidative biocorrosion in HDPE surgical implants. Further studies should confirm these pilot project results.
AbstractList	Previous histopathological studies on explanted Medpor high-density polyethylene (HDPE) facial implants indicated signs of material destruction and claimed to observe phagocytized HDPE particles within the tissue samples beside the usual type IV reaction with severe fibrosis. We examined new and explanted Medpor material with scanning electron microscopy (SEM) and energy-dispersive X-ray analysis (EDX). The implant surface of three patient-derived specimens showed significantly higher oxygenation in EDX analysis and morphological changes in SEM compared to the new unused material directly after opening of the package and after 1 year of exposure to air. Our preliminary findings indicate a possible oxidative biocorrosion in HDPE surgical implants. Further studies should confirm these pilot project results.
Author	Doeblinger, M. Draenert, M. Gosau, M. Draenert, G.F.
Author_xml	– sequence: 1 givenname: G.F. surname: Draenert fullname: Draenert, G.F. email: draenert@yahoo.com organization: Clinic for Craniomaxillofacial Surgery, University of Mainz, Augustusplatz 2, 55131 Munich, Germany – sequence: 2 givenname: M. surname: Doeblinger fullname: Doeblinger, M. organization: Department for Chemistry and Biochemistry, University of Munich, Butenandtstraße 5-13, 81377 Munich, Germany – sequence: 3 givenname: M. surname: Draenert fullname: Draenert, M. organization: Clinic for Restorative Dentistry, University of Munich, Goethestr. 70, 80336 Munich, Germany – sequence: 4 givenname: M. surname: Gosau fullname: Gosau, M. organization: Clinic for Craniomaxillofacial Surgery, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
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Cites_doi	10.1016/0142-9612(90)90049-V 10.1007/s10856-006-0015-z 10.1097/01.scs.0000168761.46700.dc 10.1023/A:1014789815441 10.1097/00007632-200310151-00006 10.1002/app.1995.070561309 10.1002/app.1964.070080419 10.1002/jbm.10203 10.1111/j.1365-2672.2005.02553.x 10.1016/j.biomaterials.2004.07.070 10.1016/j.biomaterials.2004.08.003 10.1016/0142-9612(96)83282-0 10.1016/j.biomaterials.2003.11.049 10.1097/01.sap.0000199173.73610.bc 10.1002/jbm.b.31072
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SubjectTerms	Biocorrosion Chemistry Techniques, Analytical Implant Microscopy, Electron, Scanning Oxidation Oxidation-Reduction Pilot Projects Polyethylene Polyethylene - chemistry Prostheses and Implants - ultrastructure Surface Properties X-Rays
Title	High-density polyethylene facial implants show surface oxidation in SEM and EDX examination: A pilot study
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