Controlling burst effect with PLA/PVA coaxial electrospun scaffolds loaded with BMP-2 for bone guided regeneration

Biocompatible scaffolds have been used to promote cellular growth and proliferation in order to develop grafts, prostheses, artificial skins and cartilage. Electrospinning is widely studied as a method capable of producing nanofibers which enables cell attachment and proliferation, generating a func...

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Bibliographic Details
Published in:	Materials Science & Engineering C Vol. 97; pp. 602 - 612
Main Authors:	da Silva, Talita Nascimento, Gonçalves, Raquel Pires, Rocha, Carol L., Archanjo, Bráulio S., Barboza, Carlos Augusto G., Pierre, Maria Bernadete R., Reynaud, Franceline, de Souza Picciani, Paulo Henrique
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-04-2019 Elsevier BV
Subjects:	Alcohols Alveolar bone Animals Biocompatibility Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Biomaterials Bone and Bones - physiology Bone growth Bone morphogenetic protein 2 Bone Morphogenetic Protein 2 - chemistry Bone Morphogenetic Protein 2 - pharmacology Bone surgery Cartilage Cell adhesion Cell Differentiation - drug effects Cell Line Cell Proliferation - drug effects Cell Survival - drug effects Cellular structure Contact angle Core-shell fiber Crystal structure Drug Carriers - chemistry Electrospinning Fibers Grafts Humans Hydrophobicity Materials science Mice Microscopy Model testing Morphology Nanofibers Nanofibers - chemistry Nanofibers - toxicity Organs Periodontics Polyesters - chemistry Polylactic acid Polymers Polyvinyl Alcohol - chemistry Process parameters Prostheses Prosthetics Proteins Recombinant Proteins - chemistry Recombinant Proteins - pharmacology Regeneration Regeneration - drug effects Scaffolds Skin Thermodynamic properties Thickness Tissue Engineering Tissues Transforming Growth Factor beta - chemistry Transforming Growth Factor beta - pharmacology Ultrasonic testing X-ray diffraction Electrospinning Core-shell fiber Tissue engineering Biomaterials
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