The Prognostic and Predictive Value of SOX2 + Cell Densities in Patients Treated for Colorectal Cancer

SOX2 (sex-determining region-Y homeobox-2) is a transcription factor essential for the maintenance of pluripotency and is also associated with stem-cell-like properties in preclinical cancer models. Our previous study on a cohort of stage III colon cancer patients demonstrated high SOX2 cell densiti...

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Bibliographic Details
Published in:	Cancers Vol. 12; no. 5; p. 1110
Main Authors:	Miller, Tim J, McCoy, Melanie J, Lee-Pullen, Tracey F, Anyaegbu, Chidozie C, Hemmings, Christine, Bulsara, Max K, Platell, Cameron F
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 29-04-2020 MDPI
Subjects:	5-Fluorouracil Cancer therapies Cell density Chemotherapy Colon cancer Colorectal cancer Colorectal carcinoma Homeobox Image processing Medical prognosis Oxaliplatin Patients Pluripotency Prognosis Stem cells Studies Survival analysis Transcription factors Tumors 5-fluorouracil SOX2 colorectal cancer cancer stem cell oxaliplatin chemotherapy prognosis
Online Access:	Get full text
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