Visualisation of AMPA binding sites in the brain stem of normotensive and hypertensive rats

The present study has employed in vitro receptor autoradiography with ( S)-[ 3 H ]-5-fluorowillardiine (10 nM) to visualise the presence of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) binding sites in the brain stems of adult (16–18 weeks) normotensive (Wistar–Kyoto (WKY) and Don Ryu...

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Bibliographic Details
Published in:	Brain research Vol. 834; no. 1; pp. 186 - 189
Main Authors:	Ashworth-Preece, Mark A, Chen, Feng, Jarrott, Bevyn, Lawrence, Andrew J
Format:	Journal Article
Language:	English
Published:	London Elsevier B.V 10-07-1999 Amsterdam Elsevier New York, NY
Subjects:	( S)-[ [formula omitted]]-5-Fluorowillardiine Alanine - analogs & derivatives Alanine - metabolism alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - metabolism Animals Arterial hypertension. Arterial hypotension Autoradiography Binding Sites - physiology Biological and medical sciences Blood and lymphatic vessels Brain Stem - metabolism Cardiology. Vascular system Denervation Experimental diseases Hypertension Hypertension - metabolism Male Medical sciences Neurons, Afferent - metabolism Nodose ganglion Nodose Ganglion - metabolism Nucleus tractus solitarius Pyrimidines - metabolism Rats Rats, Inbred SHR Rats, Inbred WKY Reference Values Solitary Nucleus - metabolism Tissue Distribution - physiology Vagus Nerve - cytology Vagus Nerve - metabolism α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid Hypertension α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid Autoradiography Nucleus tractus solitarius ( S)-[ 3 H ]-5-Fluorowillardiine Nodose ganglion Rat Brain stem Rodentia Central nervous system Cardiovascular disease Glutamate receptor Binding site Solitary nucleus Vertebrata AMPA receptor Mammalia Animal Brain (vertebrata)
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