Genetic Susceptibility to Mood Disorders and Risk of Stroke: A Polygenic Risk Score and Mendelian Randomization Study

Mood disorders and strokes are often comorbid, and their health toll worldwide is huge. This study characterizes prognostic and causal roles of mood disorders in stroke. We tested if genetic susceptibilities for mood disorders were associated with all strokes, ischemic strokes in the Malmö Diet and...

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Bibliographic Details
Published in:	Stroke (1970) Vol. 54; no. 5; pp. 1340 - 1346
Main Authors:	Sun, Jiangming, Borné, Yan, Edsfeldt, Andreas, Wang, Yunpeng, Pan, Mengyu, Melander, Olle, Engström, Gunnar, Gonçalves, Isabel
Format:	Journal Article
Language:	English
Published:	United States Lippincott Williams & Wilkins 01-05-2023
Subjects:	Clinical Medicine Female Genetic Predisposition to Disease Genome-Wide Association Study Humans Ischemic Stroke Klinisk medicin Medical and Health Sciences Medicin och hälsovetenskap Mendelian Randomization Analysis Mood Disorders Neurologi Neurology Polymorphism, Single Nucleotide Risk Factors Stroke - genetics cardiovascular disease prevalence mental illness patient population
Online Access:	Get full text
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