Solitary atrial myocardial metastasis revealing ileal neuroendocrine carcinoma

• Published in: Cardiovascular pathology Vol. 21; no. 4; pp. 355 - 357
• Main Authors: Meurice, Jonathan, Boulé, Stéphane, Deswarte, Guillaume, Brigadeau, François, Modine, Thomas
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-07-2012
• Subjects: Antineoplastic Agents, Hormonal - therapeutic use; Carcinoma, Neuroendocrine - diagnosis; Carcinoma, Neuroendocrine - secondary; Carcinoma, Neuroendocrine - therapy; Cardiac metastasis; Combined Modality Therapy; Echocardiography; Heart Atria - pathology; Heart neoplasms; Heart Neoplasms - diagnosis; Heart Neoplasms - secondary; Heart Neoplasms - surgery; Humans; Ileal Neoplasms - diagnosis; Ileal Neoplasms - therapy; Magnetic Resonance Imaging; Male; Middle Aged; Myocardium - pathology; Neuroendocrine carcinoma; Octreotide - therapeutic use; Pathology; Positron-Emission Tomography; Tomography, X-Ray Computed; Treatment Outcome; Cardiac metastasis; Magnetic resonance imaging; Heart neoplasms; Neuroendocrine carcinoma
• ISSN: 1054-8807; 1879-1336
• DOI: 10.1016/j.carpath.2011.10.003

Abstract A previously healthy 56-year-old man presented with chest pain. Echocardiography and cardiac magnetic resonance imaging revealed minimal pericardial effusion associated with an isolated myocardial mass, protruding into the left atrium. The tumor was surgically removed. Cardiac valve morphology was strictly normal. Histology revealed a well-differentiated neuroendocrine carcinoma. Positron emission tomography scan and thin-slice abdominal computed tomography demonstrated ileal tumor, without evidence of liver metastasis. Histological study of the removed ileal tumor confirmed a neuroendocrine carcinoma, and histology of liver biopsy was negative. Somatostatin analogue treatment was started. No tumoral recurrence was observed after 1 year of follow-up. In conclusion, we report an unusual presentation of neuroendocrine carcinoma, revealed by a large solitary atrial metastasis, in the absence of liver involvement or carcinoid syndrome.