CO2 Hydration by Mimic Zinc Complex for Active Site of Carbonic Anhydrase

The deprotonation of the zinc-bound water and the zinc-bound bicarbonate which arose from hydration of CO2 have been simulated in vitro according to the proposed mechanism for carbonic anhydrase, with the model complex of its own active site, [LZn(OH2)]2+, where L = tris(2-benzimidazolylmethyl)amine...

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Bibliographic Details
Published in:	Chemistry letters Vol. 26; no. 10; pp. 991 - 992
Main Authors:	Nakata, Kou, Uddin, M. Khabir, Ogawa, Kazuya, Ichikawa, Kazuhiko
Format:	Journal Article
Language:	English
Published:	Tokyo The Chemical Society of Japan 01-10-1997 Chemical Society of Japan
Online Access:	Get full text
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Summary:	The deprotonation of the zinc-bound water and the zinc-bound bicarbonate which arose from hydration of CO2 have been simulated in vitro according to the proposed mechanism for carbonic anhydrase, with the model complex of its own active site, [LZn(OH2)]2+, where L = tris(2-benzimidazolylmethyl)amine.
ISSN:	0366-7022 1348-0715
DOI:	10.1246/cl.1997.991