Counteraction of spaceflight-induced changes in the rat central serotonergic system by adrenalectomy and corticosteroid replacement

The effects of a 17-day spaceflight duration on serotonergic measures in various parts of rat brain have been studied (flight-SHAM group). The contribution of the activation of the hypothalamo-pituitary-adrenal axis (HPA) related to the response of the central serotonin system was evaluated in adren...

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Bibliographic Details
Published in:	Neurochemistry international Vol. 33; no. 4; pp. 375 - 382
Main Authors:	Blanc, S, Somody, L, Gharib, A, Gauquelin, G, Gharib, C, Sarda, N
Format:	Journal Article
Language:	English
Published:	Oxford Elsevier Ltd 01-10-1998 Elsevier
Subjects:	Adrenal Glands - anatomy & histology Adrenalectomy Aldosterone - blood Animals Biological and medical sciences Brain - drug effects Brain - metabolism Brain - physiology Corticosterone - blood Corticosterone - pharmacology Fundamental and applied biological sciences. Psychology General aspects. Hormone interactions. Hormone actions on several organ systems. Adaptive reactions Male Organ Size Osmolar Concentration Rats Rats, Sprague-Dawley Serotonin - physiology Space Flight Space life sciences Thymus Gland - anatomy & histology Tryptophan - metabolism Vertebrates: endocrinology Corticosteroid Rat Hypothalamohypophysoadrenal axis Serotonin Rodentia Environmental factor Space flight Stress Adrenalectomy Vertebrata Mammalia Neurotransmitter Microgravity
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