Levodopa-induced dyskinesia in an autopsy-proven case of progressive supranuclear palsy

• Published in: Movement disorders Vol. 17; no. 5; pp. 1089 - 1090
• Main Authors: Kim, Jong-Min, Lee, Ki Hyeong, Choi, Yoon-La, Choe, Gi Yeong, Jeon, Beom S.
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 01-09-2002; Wiley
• Subjects: Antiparkinson Agents - adverse effects; Antiparkinson Agents - therapeutic use; Biological and medical sciences; Brain - pathology; Culture Techniques; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Drug toxicity and drugs side effects treatment; Dyskinesia, Drug-Induced - diagnosis; Dyskinesia, Drug-Induced - etiology; Fatal Outcome; Female; Humans; Levodopa - adverse effects; Levodopa - therapeutic use; Medical sciences; Middle Aged; Neurofibrillary Tangles - pathology; Neurology; Pharmacology. Drug treatments; Supranuclear Palsy, Progressive - drug therapy; Supranuclear Palsy, Progressive - pathology; Toxicity: nervous system and muscle; Human; Nervous system diseases; Supranuclear ophthalmoplegia; Antiparkinson agent; Video recording; Cerebral disorder; Involuntary movement; Case study; Progressive; Eye disease; Chemotherapy; Autopsy; Central nervous system disease; Complication; Degenerative disease; Levodopa; Oculomotor syndrome; Neurological disorder; Brain stem syndrome; Extrapyramidal syndrome; Dyskinesia
• ISSN: 0885-3185; 1531-8257
• DOI: 10.1002/mds.10246

It is common for patients with idiopathic Parkinson's disease to develop levodopa‐induced dyskinesia. This report provides what we believe is the first videotape presentation of levodopa‐induced dyskinesia in a patient with progressive supranuclear palsy. To our knowledge, there is only one previous report of an autopsy‐proven case of this kind. © 2002 Movement Disorder Society