Hepatic Activin E mediates liver-adipose inter-organ communication, suppressing adipose lipolysis in response to elevated serum fatty acids

The liver is a central regulator of energy metabolism exerting its influence both through intrinsic processing of substrates such as glucose and fatty acid as well as by secreting endocrine factors, known as hepatokines, which influence metabolism in peripheral tissues. Human genome wide association...

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Bibliographic Details
Published in:	Molecular metabolism (Germany) Vol. 78; p. 101830
Main Authors:	Griffin, John D, Buxton, Joanne M, Culver, Jeffrey A, Barnes, Robert, Jordan, Emily A, White, Alexis R, Flaherty, Stephen E, Bernardo, Barbara, Ross, Trenton, Bence, Kendra K, Birnbaum, Morris J
Format:	Journal Article
Language:	English
Published:	Germany Elsevier 01-12-2023
Subjects:	Activins - metabolism Adipose tissue Adipose Tissue - metabolism Adiposity Animals Diabetes Fatty Acids - metabolism Fatty Acids, Nonesterified - blood Fatty Acids, Nonesterified - metabolism Hepatocytes - metabolism Humans Inhibin-beta Subunits - genetics Inhibin-beta Subunits - metabolism Lipolysis Liver - metabolism Male Mice Mice, Inbred C57BL Mice, Knockout Obesity Obesity Adipose tissue Diabetes Lipolysis
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