Evaluation of alveolar socket response to Angelus MTA and experimental light-cure MTA

• Published in: Oral surgery, oral medicine, oral pathology, oral radiology and endodontics Vol. 110; no. 5; pp. e93 - e97
• Main Authors: Gomes-Filho, João Eduardo, PhD, de Moraes Costa, Mariana Teixeira, PhD, Cintra, Luciano Tavares Ângelo, PhD, Lodi, Carolina Simonetti, MSc, Duarte, Paulo Carvalo Tobias, MSc, Okamoto, Roberta, PhD, Bernabé, Pedro Felício Estrada, PhD, Nery, Mauro Juvenal, PhD, Cannon, Mark, DDS, MSc
• Format: Journal Article
• Language: English
• Published: United States Mosby, Inc 01-11-2010
• Subjects: Aluminum Compounds - pharmacology; Animals; Biocompatible Materials - pharmacology; Calcification, Physiologic - drug effects; Calcification, Physiologic - physiology; Calcium Compounds - pharmacology; Dentistry; Drug Combinations; Fibroblasts - pathology; Fibrosis; Giant Cells - pathology; Lymphocytes - pathology; Macrophages - pathology; Male; Maxilla - drug effects; Maxilla - pathology; Necrosis; Osteogenesis - drug effects; Osteogenesis - physiology; Oxides - pharmacology; Polyethylene - pharmacology; Prostheses and Implants; Rats; Rats, Wistar; Root Canal Filling Materials - pharmacology; Silicates - pharmacology; Surgery; Time Factors; Tooth Socket - drug effects; Tooth Socket - pathology
• ISSN: 1079-2104; 1528-395X
• DOI: 10.1016/j.tripleo.2010.05.065

Objective The aim of this study was to evaluate the rat alveolar socket response to implanted polyethylene tubes filled with a light-cured MTA or Angelus MTA. Study design Fifty-seven Wistar rats received an implant filled with one of the materials in the dental socket of the right central incisor. After 30, 60, and 90 days, animals were killed, and the right hemimaxillas were removed and processed to be analyzed on light microscopy. After embedding in paraffin, 6-μm-thick sections were obtained and stained with hematoxylin and eosin. Qualitative and quantitative analyses of the reaction were performed. Results It was observed that the light-cured MTA presented a similar response compared with Angelus MTA, characterized by the reduction of the chronic inflammatory response and organization of the alveolar bone close to the materials, especially at the 90th day of observation. Conclusions It was concluded that both materials were well accepted by the alveolar tissue of rats, with the formation of mineralized tissue close to the materials.