Kinetic modelling of Lactobacillus casei ssp. rhamnosus growth and lactic acid production in batch cultures under various medium conditions

• Published in: Biotechnology letters Vol. 27; no. 22; pp. 1785 - 1789
• Main Authors: BEN YOUSSEF, Cherif, GOMA, Gerard, OLMOS-DICHARA, Alejandro
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer 01-11-2005; Springer Nature B.V
• Subjects: Acid production; Acids; Batch processing; Biological and medical sciences; Biotechnology; Cell culture; Cell Culture Techniques - methods; Cell growth; Cell Proliferation; Computer Simulation; Culture Media - metabolism; Fundamental and applied biological sciences. Psychology; Kinetics; Lactic Acid - biosynthesis; Lactobacillus casei; Lactobacillus casei - growth & development; Lactobacillus casei - metabolism; Metabolic Clearance Rate; Models, Biological; Yeasts; Culture medium; Lactic acid bacteria; batch culture; Lactobacillus casei; Growth; Kinetic model; kinetic modelling; Batchwise; Production; Bacteria; Lactobacillaceae; Lactic acid; Culture
• ISSN: 0141-5492; 1573-6776
• DOI: 10.1007/s10529-005-3557-0

Enrichment of medium with yeast extract and tryptone increased growth and lactic acid production in batch cultures of Lactobacillus casei ssp. rhamnosus. A reliable kinetic model that explicitly expresses the strong relationship between microbial growth, lactic acid production and medium enrichment is provided and validated using experimental data obtained with six different medium compositions.