Role of Selenium Deficiency in Pediatrics with Acquired Hypothyroidism
Although selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare studies. This study aimed to evaluate role of selenium deficiency in children and adolescents with acquired hypothyroidism. This case and control study was con...
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| Published in: | International journal of preventive medicine Vol. 12; no. 1; p. 83 |
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| Main Authors: | , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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Iran
Wolters Kluwer - Medknow
01-01-2021
Wolters Kluwer Medknow Publications |
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| Abstract | Although selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare studies. This study aimed to evaluate role of selenium deficiency in children and adolescents with acquired hypothyroidism.
This case and control study was conducted on 60 acquired hypothyroidism and 60 healthy children who had been referred to the pediatrics endocrine clinic in
, from November 2018 to April 2019. Some information such as age, gender, weight, height, duration of disease, and level of plasma selenium were recorded. Plasma selenium level was measured by atomic absorption spectrophotometer. Data were analyzed using SPSS software 21.0.
The mean of selenium level in the case and control groups were 93.77 ± 24.90 μg/dl and 85.96 ± 25.20 μg/dl, respectively. There was no significant difference between the two groups in the mean levels of selenium. Independent
-test showed no significant difference in the mean levels of selenium in male and female samples in the case group, but this difference was significant in the control group.
Selenium deficiency may not have significant role as a cause of acquired hypothyroidism in pediatric and adolescent age group, in south of
. Thus, it does not seem necessary to routinely check the level of selenium for patients with thyroid dysfunction. |
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| AbstractList | Although selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare studies. This study aimed to evaluate role of selenium deficiency in children and adolescents with acquired hypothyroidism.
This case and control study was conducted on 60 acquired hypothyroidism and 60 healthy children who had been referred to the pediatrics endocrine clinic in
, from November 2018 to April 2019. Some information such as age, gender, weight, height, duration of disease, and level of plasma selenium were recorded. Plasma selenium level was measured by atomic absorption spectrophotometer. Data were analyzed using SPSS software 21.0.
The mean of selenium level in the case and control groups were 93.77 ± 24.90 μg/dl and 85.96 ± 25.20 μg/dl, respectively. There was no significant difference between the two groups in the mean levels of selenium. Independent
-test showed no significant difference in the mean levels of selenium in male and female samples in the case group, but this difference was significant in the control group.
Selenium deficiency may not have significant role as a cause of acquired hypothyroidism in pediatric and adolescent age group, in south of
. Thus, it does not seem necessary to routinely check the level of selenium for patients with thyroid dysfunction. BACKGROUNDAlthough selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare studies. This study aimed to evaluate role of selenium deficiency in children and adolescents with acquired hypothyroidism.METHODSThis case and control study was conducted on 60 acquired hypothyroidism and 60 healthy children who had been referred to the pediatrics endocrine clinic in Shiraz, Iran, from November 2018 to April 2019. Some information such as age, gender, weight, height, duration of disease, and level of plasma selenium were recorded. Plasma selenium level was measured by atomic absorption spectrophotometer. Data were analyzed using SPSS software 21.0.RESULTSThe mean of selenium level in the case and control groups were 93.77 ± 24.90 μg/dl and 85.96 ± 25.20 μg/dl, respectively. There was no significant difference between the two groups in the mean levels of selenium. Independent t-test showed no significant difference in the mean levels of selenium in male and female samples in the case group, but this difference was significant in the control group.CONCLUSIONSelenium deficiency may not have significant role as a cause of acquired hypothyroidism in pediatric and adolescent age group, in south of Iran. Thus, it does not seem necessary to routinely check the level of selenium for patients with thyroid dysfunction. Background: Although selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare studies. This study aimed to evaluate role of selenium deficiency in children and adolescents with acquired hypothyroidism. Methods: This case and control study was conducted on 60 acquired hypothyroidism and 60 healthy children who had been referred to the pediatrics endocrine clinic in Shiraz, Iran, from November 2018 to April 2019. Some information such as age, gender, weight, height, duration of disease, and level of plasma selenium were recorded. Plasma selenium level was measured by atomic absorption spectrophotometer. Data were analyzed using SPSS software 21.0. Results: The mean of selenium level in the case and control groups were 93.77 ± 24.90 μg/dl and 85.96 ± 25.20 μg/dl, respectively. There was no significant difference between the two groups in the mean levels of selenium. Independent t-test showed no significant difference in the mean levels of selenium in male and female samples in the case group, but this difference was significant in the control group. Conclusion: Selenium deficiency may not have significant role as a cause of acquired hypothyroidism in pediatric and adolescent age group, in south of Iran. Thus, it does not seem necessary to routinely check the level of selenium for patients with thyroid dysfunction. |
| Author | Amirhakimi, Anis Rostami, Khashayar Moravej, Hossein Yazdani, Negar Rakhshandehroo, Shahrokh Moghtaderi, Mozhgan Mazlumi-Abrazgah, Shokroallah Ilkhanipoor, Homa |
| AuthorAffiliation | 3 Managing Director of Peyvand Pathobiology and Genetics Laboratory, Shiraz University of Medical Sciences, Shiraz, Iran 1 Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 4 Department of Pediatric, Shiraz University of Medical Sciences, Shiraz, Iran 2 Department of Pediatric Endocrinology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran |
| AuthorAffiliation_xml | – name: 4 Department of Pediatric, Shiraz University of Medical Sciences, Shiraz, Iran – name: 2 Department of Pediatric Endocrinology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran – name: 1 Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran – name: 3 Managing Director of Peyvand Pathobiology and Genetics Laboratory, Shiraz University of Medical Sciences, Shiraz, Iran |
| Author_xml | – sequence: 1 givenname: Hossein surname: Moravej fullname: Moravej, Hossein organization: Department of Pediatric Endocrinology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran – sequence: 2 givenname: Shahrokh surname: Rakhshandehroo fullname: Rakhshandehroo, Shahrokh organization: Managing Director of Peyvand Pathobiology and Genetics Laboratory, Shiraz University of Medical Sciences, Shiraz, Iran – sequence: 3 givenname: Homa surname: Ilkhanipoor fullname: Ilkhanipoor, Homa organization: Department of Pediatric Endocrinology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran – sequence: 4 givenname: Anis surname: Amirhakimi fullname: Amirhakimi, Anis organization: Department of Pediatric Endocrinology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran – sequence: 5 givenname: Khashayar surname: Rostami fullname: Rostami, Khashayar organization: Department of Pediatric, Shiraz University of Medical Sciences, Shiraz, Iran – sequence: 6 givenname: Negar surname: Yazdani fullname: Yazdani, Negar organization: Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran – sequence: 7 givenname: Mozhgan surname: Moghtaderi fullname: Moghtaderi, Mozhgan organization: Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran – sequence: 8 givenname: Shokroallah surname: Mazlumi-Abrazgah fullname: Mazlumi-Abrazgah, Shokroallah organization: Department of Pediatric Endocrinology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34584649$$D View this record in MEDLINE/PubMed |
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| Keywords | hashimoto disease selenium selenoproteins hypothyroidism Deficiency |
| Language | English |
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| Snippet | Although selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare studies. This... BACKGROUNDAlthough selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare studies.... Background: Although selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare... |
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| Title | Role of Selenium Deficiency in Pediatrics with Acquired Hypothyroidism |
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