Blockade of astrocytic activation delays the occurrence of severe hypoxia‐induced seizure and respiratory arrest in mice

Seizures are induced when subjects are exposed to severe hypoxia. It is followed by ventilatory fall‐off and eventual respiratory arrest, which may underlie the pathophysiology of death in patients with epilepsy and severe respiratory disorders. However, the mechanisms of hypoxia‐induced seizures ha...

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Bibliographic Details
Published in:	Journal of comparative neurology (1911) Vol. 528; no. 8; pp. 1257 - 1264
Main Authors:	Fukushi, Isato, Takeda, Kotaro, Uchiyama, Makoto, Kurita, Yuki, Pokorski, Mieczyslaw, Yokota, Shigefumi, Okazaki, Shuntaro, Horiuchi, Jouji, Mori, Yasuo, Okada, Yasumasa
Format:	Journal Article
Language:	English
Published:	Hoboken, USA John Wiley & Sons, Inc 01-06-2020 Wiley Subscription Services, Inc
Subjects:	Acids arundic acid astrocyte Astrocytes Convulsions & seizures EEG Epilepsy Hypoxia hypoxic ventilatory depression Mechanical ventilation Neurological diseases RRID:AB_477010 RRID:SCR_001620 RRID:SCR_001622 Seizures SUDEP Ventilation epilepsy hypoxic ventilatory depression RRID:AB_477010 RRID:SCR_001620 SUDEP arundic acid RRID:SCR_001622 astrocyte
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