Don’t be fooled by the fat: A rare case of renal cell carcinoma with intratumoural fat
Angiomyolipoma (AML) is a benign renal tumour composed of fat, smooth muscle and blood vessels. Radiologic evidence of macroscopic fat within a solid renal lesion on computed tomography was historically thought to be pathognomonic for this condition. Herein, we report a case of an incidental solid r...
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| Published in: | Urology case reports Vol. 30; p. 101112 |
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| Language: | English |
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| Abstract | Angiomyolipoma (AML) is a benign renal tumour composed of fat, smooth muscle and blood vessels. Radiologic evidence of macroscopic fat within a solid renal lesion on computed tomography was historically thought to be pathognomonic for this condition. Herein, we report a case of an incidental solid renal cell mass with multiple foci of intra-tumoral fat, which was shown to be a clear cell renal cell carcinoma (RCC) at nephrectomy. Macroscopic fat within solid renal lesions does not exclude malignancy, evaluation of other radiologic features is necessary when RCC is suspected. |
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| AbstractList | Angiomyolipoma (AML) is a benign renal tumour composed of fat, smooth muscle and blood vessels. Radiologic evidence of macroscopic fat within a solid renal lesion on computed tomography was historically thought to be pathognomonic for this condition. Herein, we report a case of an incidental solid renal cell mass with multiple foci of intra-tumoral fat, which was shown to be a clear cell renal cell carcinoma (RCC) at nephrectomy. Macroscopic fat within solid renal lesions does not exclude malignancy, evaluation of other radiologic features is necessary when RCC is suspected. |
| ArticleNumber | 101112 |
| Author | Morris, Hannah McLeod, Nicholas Delprado, Warick March, Brayden |
| AuthorAffiliation | b School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW, 2308, Australia c Hunter Medical Research Institute, University of Newcastle, New Lambton, NSW, 2305, Australia a Department of Urology, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia d Douglass Hanly Moir Pathology, Macquarie Park, NSW, 2113, Australia f Macquarie University Hospital, Macquarie University, Sydney, Australia e School of Medicine, University of Notre Dame, Sydney, Australia |
| AuthorAffiliation_xml | – name: e School of Medicine, University of Notre Dame, Sydney, Australia – name: a Department of Urology, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia – name: c Hunter Medical Research Institute, University of Newcastle, New Lambton, NSW, 2305, Australia – name: b School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW, 2308, Australia – name: d Douglass Hanly Moir Pathology, Macquarie Park, NSW, 2113, Australia – name: f Macquarie University Hospital, Macquarie University, Sydney, Australia |
| Author_xml | – sequence: 1 givenname: Hannah surname: Morris fullname: Morris, Hannah organization: Department of Urology, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia – sequence: 2 givenname: Brayden surname: March fullname: March, Brayden email: brayden.march@uon.edu.au organization: Department of Urology, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia – sequence: 3 givenname: Warick surname: Delprado fullname: Delprado, Warick organization: Douglass Hanly Moir Pathology, Macquarie Park, NSW, 2113, Australia – sequence: 4 givenname: Nicholas surname: McLeod fullname: McLeod, Nicholas organization: Department of Urology, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia |
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| References | Garin, Marco, Salva, Serrano, Bondia, Pacheco (bib2) 2007; 80 Helenon, Chretien, Paraf, Melki, Denys, Moreau (bib3) 1993; 188 Schuster, Ferguson, Baker, Schaldenbrand, Solomon (bib5) 2004; 183 Chen, Tang, Wu (bib4) 2013; 14 Prando (bib1) 1991; 156 Garin (10.1016/j.eucr.2019.101112_bib2) 2007; 80 Helenon (10.1016/j.eucr.2019.101112_bib3) 1993; 188 Schuster (10.1016/j.eucr.2019.101112_bib5) 2004; 183 Chen (10.1016/j.eucr.2019.101112_bib4) 2013; 14 Prando (10.1016/j.eucr.2019.101112_bib1) 1991; 156 |
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| Title | Don’t be fooled by the fat: A rare case of renal cell carcinoma with intratumoural fat |
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