ChlorTox Base – a useful source of information on popular reagents in terms of chemical hazards and greenness assessment

• Published in: Green Analytical Chemistry Vol. 6; p. 100065
• Main Authors: Nowak, Paweł Mateusz, Bis, Alicja, Zima, Aleksandra
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01-09-2023; Elsevier
• Subjects: Chlortox base; Chlortox scale; Green analytical chemistry; Green chemistry; Greenness assessment; Unified greenness theory (UG-theory); White analytical chemistry; UG-theory; White analytical chemistry; DES; Greenness assessment; Unified greenness theory (UG-theory); Chlortox scale; Green chemistry; Green analytical chemistry; Chlortox base
• ISSN: 2772-5774; 2772-5774
• DOI: 10.1016/j.greeac.2023.100065

•674 chemical substances characterized in terms of hazards.•WHN values as the main parameter determining how hazardous in overall is given reagent.•Easy use of the chlortox scale for method evaluation (unified chemical hazard data).•Additional analysis of selected parameters and correlations.
ChlorTox Base is a database on the chemical hazards of popular reagents used in the chemical laboratory, derived from available safety data sheets published by various manufacturers. 1,388 sheets and 674 different chemicals were reviewed. Weighted hazards number (WHN) was used as the main parameter reflecting the “greenness” of particular substances, understood as a spectrum and severity of various forms of adverse health, safety, and environmental impacts. The presented WHN values ​​can be directly used in the greenness assessment and evaluation, for instance in the ChlorTox Scale – a simple tool for estimating chemical risk of laboratory method in accordance with the postulates of the Unified Greenness Theory.
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