Base-free oxidation of thiols to disulfides using selenium ionic liquid

We present here the results on the use of 1-n-butyl-3-methylimidazolium methylselenite, [bmim][SeO2(OCH3)], in the synthesis of symmetrical disulfides starting from thiols. This efficient and improved method is general for aromatic, aliphatic, and functionalized thiols affording the disulfides in go...

Full description

Saved in:

Bibliographic Details
Published in:	Tetrahedron letters Vol. 52; no. 5; pp. 640 - 643
Main Authors:	Thurow, Samuel, Pereira, Vanda A., Martinez, Débora M., Alves, Diego, Perin, Gelson, Jacob, Raquel G., Lenardão, Eder J.
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 02-02-2011
Subjects:	Disulfides Oxidation Selenium ionic liquid Oxidation Disulfides Selenium ionic liquid
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	We present here the results on the use of 1-n-butyl-3-methylimidazolium methylselenite, [bmim][SeO2(OCH3)], in the synthesis of symmetrical disulfides starting from thiols. This efficient and improved method is general for aromatic, aliphatic, and functionalized thiols affording the disulfides in good to excellent yields after easy work up. The use of a microwave accelerates the reaction and the [bmim][SeO2(OCH3)] was reused for further oxidation reactions.
ISSN:	0040-4039 1873-3581
DOI:	10.1016/j.tetlet.2010.11.158