Quantum Dots: Emerging applications in urologic oncology

• Published in: Urologic oncology Vol. 26; no. 1; pp. 86 - 92
• Main Authors: Shi, Chunmeng, Ph.D, Zhu, Ying, M.P.H, Cerwinka, Wolfgang H., M.D, Zhau, Haiyen E., Ph.D, Marshall, Fray F., M.D, Simons, Jonathan W., M.D, Nie, Shuming, Ph.D, Chung, Leland W.K., Ph.D
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 2008
• Subjects: Biomarkers, Tumor - analysis; Cancer imaging; Cell signaling; EMT; Gene Expression Regulation, Neoplastic; Humans; Male; Nanoparticles; Prognosis; Prostate cancer; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - genetics; Quantum dots; Quantum Theory; Urologic Neoplasms - diagnosis; Urologic Neoplasms - therapy; Urology; Quantum dots; Cancer imaging; Prostate cancer; EMT; Cell signaling
• ISSN: 1078-1439; 1873-2496
• DOI: 10.1016/j.urolonc.2007.03.018

Abstract Quantum dots (QDs), nanometer-sized fluorescent probes with unique optical and electronic properties, offer a promising and powerful tool for cancer imaging and diagnostics. For the past few years, QDs were actively developed for biomolecular profiling of cancer biomarkers, in vivo tumor imaging, and even targeted drug delivery. These emerging applications are currently being improved and integrated into clinical practice. In this article, we describe the development of multifunctional QDs and their potential applications in oncology, with a particular emphasis on the diagnosis, prognosis, and treatment of urologic cancers.